Abstract: Structure is a key parameter that determines the physical properties and functions of molecules and materials. Yet, there are still several unique structures that are difficult to synthesize in medium- and macromolecules. We are particularly interested in the topology of these molecules, and I will introduce our two recent examples. One is the synthesis…
Photoswitchable molecules can reversibly interconvert between two different isomers. With new applications for photoswitches constantly emerging, the necessity arises to continue to develop photoswitches with different properties than the already established ones. We have developed a versatile synthesis for macrocyclic azobenzenes, which allows for facile modification of these photoswitches. One example shows high chemical stability,…
Online assessments where there is a clear ‘correct’ answer are susceptible to students working together, sharing (or even selling) answers. The challenge we faced was to take a 1 hour, closed-book invigilated exam and turn it into a 24 hour, open book, non-invigilated exam. Our approach was to provide every student with their own data…
Over the past decade, photocatalysis has become a powerful synthetic tool, offering novel reaction pathways that were previously inaccessible by other methods. Our research group develops photocatalytic approaches to the activation of relatively strong bonds (including C-O[1] or C-C bonds), aiming at novel C-C bond forming reactions using such “alternative” substrates as versatile coupling partners.…
This event is open to academic staff, final year undergraduate project students, MSc students, PhD students and postdoctoral researchers. The talk, titled Porous carbons as sustainable energy materials, will explore the conversion of biomass and other waste carbonaceous matter to porous carbons with optimised properties for use in energy storage applications, and specifically the storage…
Around 111,500 employees contribute to the BASF Group’s success worldwide. Our business is divided into the Chemicals, Materials, Industrial Solutions, Surface Technologies, Nutrition & Care and Agricultural Solutions segments. Our chemistry is used in almost all industries. Together with our customers we aim to overcome challenges that can be solved with chemistry. With our products…
Zinc mis-regulation is associated with a wide range of disease states and there is an ongoing need to study the behaviour of ‘mobile’ or ‘free’ zinc to better understand its role in their development and progression. Small molecule fluorescent probes are commonly used for this purpose, and a significant number of probes have been developed…
Title and Abstract — TBC For details regarding the speaker and their research please see their website.
Title and Abstract — TBC For details regarding the speaker and their research please see their website.
Abstract: GTP hydrolysis is central to biology, being involved in regulating a wide range of cellular processes. In recent years, there has been more success in the potential therapeutic strategy to target KRas oncoprotein–driven cancers. However, multiple mechanistic possibilities of GTPases (Ras, Rho, Ran, Rab, etc) catalysed hydrolysis accelerated by GTPase activating protein (GAP) both…